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CBDP: What is it and what are its effects?

close-ups A cbd shoot held by gloved hands

After our article on 10-OH-HHC, we continue our tour of CBD counterparts with CBDP.

With its full name of "cannabidiphorol", CBDP was discovered not so long ago, at the same time as its mirror cannabinoid tetrahydro version: THCP (or tetrahydrocannabiphorol for those in the know).

For those who may have missed the story of the discovery of these molecules, we'll give you a quick recap before presenting the effects and preliminary research on the subject of CBD-P.

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What is CBDP?

While CBDV, THCV and H2CBD have been known since the mid-20th century, CBDP and THCP were only discovered in 2019. The reason for this is their very low natural occurrence (less than 1%).

The discovery was made by a team of Italian researchers at the University of Modena, led by Professor Giuseppe Cannazza.

Like THCP, CBDP differs little from its counterpart. In fact, the only difference lies in its side chain. CBDP has 7 hydrocarbons in this chain, while CBD has only 5. It's because of this difference with CBD that CBD-P is also known as CBD-C7, C7-CBD or CBD-heptyl.

More than just a variation in name, this longer hydrocarbon chain also results in a difference in the interaction of this molecule with the endocannabinoid system, which obviously translates into different effects.

What are the effects of CBDP?

We're going to talk about the potential effects of CBDP, but as always, it's important to bear in mind that we know very little about the molecule, and that the effects we're going to talk about are based on consumer feedback or preliminary research. There is therefore no clinical certainty to support the effects listed below.

That being said, CBDP seems to have quite a few differences compared to CBD. First, it appears that CBDP does not produce psychotropic or euphoric effects , but it seems capable of more pronounced psychoactive effects than CBD, which translate into:

  • Greater antioxidant and analgesic potential
  • Greater anxiolytic and antidepressant properties
  • A greater sense of hunger

It would also appear that CBDP has a more sustained interaction with other cannabinoids, therefore stronger entourage effects.

 

chemical structure CBD vs cbdp

CBDP: Preliminary Studies

Like CBD, CBDV, and all other cannabinoids in the CBD family, CBDP does not have psychotropic effects and, currently, does not appear to cause any particular undesirable side effects (except in cases of intolerance), nor any habit-forming or addictive effects. This difference from most THC molecules makes CBD molecules very good candidates for clinical research.

To date, there appears to be only one study that has specifically attempted to analyze CBDP's behavior and efficacy. This study set out to explore the potential of CBDP in the treatment of breast cancer.

Indeed, in recent years a study conducted in 2019 demonstrated that phytocannabinoids (CBD, THC, TCBA and CBDA as well as CBN) showed selective anticancer activity against several types of cancer (notably on three different lung cancer cell lines, and those of breast cancer). (1)

In addition, two other studies have shown that cannabinoids enhance the action of chemotherapy treatments. Particularly in the treatment of tumors refractory to therapy. (2)

The study we are interested in was able to prove that the longer carbon chain of CBDP, which we have discussed, multiplied the effects of the molecule in the context of breast cancer treatment .(3)

Nevertheless, these supposed effects are still only conjecture. Although they have been noted in various research studies, no real applications have yet been carried out.

 

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  • Production and legality

    CBDP occurs naturally in hemp, but in insufficient quantities to be marketed as such. The CBDP you'll find on the market is synthesized in the laboratory. It is therefore a semi-synthetic molecule.

    CBDP is obtained by isomerizing CBD distillate. In simple terms, this involves rearranging the atoms within the CBD molecule to obtain CBDP. This process has been known for over two centuries and is commonly used in several industries, such as food and beverage. It is notably through this principle that we obtain the infamous trans fatty acids and glucose-fructose syrup, which is an ingredient in a multitude of everyday products.

    As for the molecule's legality, in France,CBDP is totally legal as long as it contains less than 0.3% THC. This is also the case in most European Union countries.

    Our conclusion on CBDP

    From what we have seen, CBDP could be included in the composition of several products in the future.

    Nevertheless, as with all other cannabinoids known to date, a great deal of research remains to be carried out, particularly into their medium- and long-term effects, different routes of application, different dosages, and the total absence of harmful effects and side-effects, in order to be certain of the compound's therapeutic potential.

    Until then, keep checking the CBDOO blog to stay up-to-date on all the latest CBD news!

    Sources

    1. [1]
    2. [2]
    3. [3]

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